Eur. Phys. J. AP 12, 217-222 (2000)
https://doi.org/10.1051/epjap:2000190

Development of a linear transient model for stimulation of isolated cardiac cells^*

¹ Laboratoire d'Instrumentation Micro-Informatique et d'Electronique, LIME/UJFG, BP 53X, 38041 Grenoble, France
² INSERM - Cardiologie Théorique - CHU Pitié Salpétrière, 91 boulevard de l'Hôpital, 75634 Paris Cedex 13, France
³ LBFA/UJFG, BP 53, 38041 Grenoble Cedex 9, France

Corresponding authors: pascale.pham@cea.fr cauffet@leg.ensieg.inpg.fr

Received: 15 May 2000
Revised: 17 October 2000
Accepted: 17 October 2000
Published online: 15 December 2000

Abstract

Isolated cardiac cells stimulators design can be aided by numerical tools based on the behavior model. The linear model (RC circuit) is the most straightforward model for describing the electrical membrane cell behavior for an external electrical stimulation: however, an adjustment is necessary to make it competent to describe correctly the different types of excitation variability experimentally observed. A Linear Transient Model is presented, solved by the Finite Element Method.