https://doi.org/10.1051/epjap:2002049
Analysis of pulsed photoacoustic signal: theoretical study of the diffusion of chromophores in the human skin
1
Faculté des Sciences de Meknès, Département de Physique, BP 4010 Beni M'hamed, Meknès,
Morocco
2
École Nationale des Sciences Appliquées de Tanger, Université Abdelmalek Essaadi, BP
416, Tanger principal, Tanger, Morocco
3
Faculté des Sciences de Kénitra, Université Ibn Tofail, Faculté des Sciences, BP 133, 14000
Kénitra, Morocco
Corresponding author: nabil_benamar@yahoo.fr
Received:
12
December
2001
Revised:
29
March
2002
Accepted:
2
April
2002
Published online:
28
June
2002
Pulsed photoacoustic spectroscopy (PPAS) provides a convenient means for in vivo and in situ monitoring of human skin properties and surface concentrations of locally applied substances, such as drugs and cosmetics. In this article, we applied the one-dimensional theoretical model of Mandelis and Royce (J. Appl. Phys. 50, 6 (1979)) to simulate the photoacoustic response of human skin and diffusion phenomena through it, for various optical absorption coefficients and sample thicknesses. This approach is analyzed through the temperature and pressure variations in the photoacoustic cell.
PACS: 82.80.Kq – Energy-conversion spectro-analytical methods (e.g., photoacoustic, photothermal, and optogalvanic spectroscopic methods) / 87.64.-t – Spectroscopic and microscopic techniques in biophysics and medical physics / 87.15.Aa – Theory and modeling; computer simulation
© EDP Sciences, 2002
